Endocannabinoid System and Endocannabinoid Deficiency

It has become common knowledge that both animals and human beings have this one vital component, that was never taught to us in schools. Out of all the 11 major bodily systems, i.e. respiratory system, cardiovascular, sensory, nervous system, reproductive system, endocrine system, and digestive system to name a few, this was one that was left out, or rather, was not known about till only after the 1980s. Functionalities thereof and the other remaining ones can be found on this website.

We have numerous works of literature about how this to help our bodies become stronger and more susceptible to illness, however when the Endocannabinoid System (ECS) has issues with it, there is a term that defines it as an Endocannabinoid Deficiency. Much in the same way we suffer from various illnesses, if the ECS does not function properly, it leads to various other health conditions, and this should give you an indication of how important it look after it.
But if we have never heard about it until now and may have symptoms of it, how do we know to look after it properly? Well, this article will give you some information about that, in the hopes of kicking you off to a good start.

First and Foremost

Firstly, how can we tell we may have a deficiency? By the low levels of endocannabinoids and cannabinoid receptors in our bodies. Because these are one of the main components responsible for treating many health issues it is fundamental to make sure it functions properly.

In other words, if the below mechanisms function properly, so will your body. Let’s look at them briefly.
Enzymes – The metabolic composites that are accountable for forming and breaking down of any cannabinoids from external elements such as CBD for instance.

Endocannabinoids – The body produces these naturally and anyone (man or animal) that has an ECS will have it within their systems naturally.

Cannabinoid receptors – These interact with and bind together with the phytocannabinoids if any, and the endocannabinoids thus putting into motion the various processes in the ECS.

The Deficiency Itself – What We know

Also known as, clinical endocannabinoid deficiency (CED or CECD), this condition was first coined by a popular researcher at the time (2001), called Dr. Ethan Russo. After this, it was brought to light a few years later and in 2004. What researchers found is that this condition involved a general disorder of the cannabinoid receptors CB1 and CB2 https://www.fundacion-canna.es/en/failure-endocannabinoid-system-theory-or-reality.

When people suffer from this it can lead to various impairments such as fibromyalgia, migraines, IBS or Irritable bowel syndrome, and various other inflammatory ailments.
According to the recent study done that showed the likelihood of the underlying pathophysiology, it suggests that the symptoms of all the above are very similar and a clinical deficiency may be the problem. When looked at further it had seen that exogenous cannabinoid treatment i.e. taking CBD supplements, had benefits to these symptoms.
Clinical data has provided various other positive results such as benefits provided to sleep improvements, depression, motion sickness, migraine, decreasing pain, and all were linked to the ECS. When additional help was provided externally, it helped heal it.

Other reasons for this deficiency could be genetic. But the commonality between many subjects who had the same weakness in their systems showed the same for their mood, sleep, and pain threshold. All were weakened too.

The Solution

In the same study as mentioned above, the introduction of Cannabis, was seen to have the best results so far and you can look here for further information on this. It was posed as the most effective intervention in the 19th century and till date remains the same. Even with IBS, which is a very common condition in many people, it showed improvements. It was shown to improve the microbiome of the gut, which is where this condition stems from and altered the microflora balance of obese patients as well.
This enhanced the overall gut-health and weight gain was significantly reduced even when a high-fat diet was introduced. IBS, which is characterized as an imbalance in the gut, in other words, the gastrointestinal (GI) disorder that causes pain, discomfort, and diarrhea or constipation, has been seen to occur as a result of a few things including anxiety.
The above is just one example of what has helped and it has been a recommendation of various researchers and medical professionals, some of which have agreed that introducing CBD or cannabis by-products to your ECS will do more healing than harm to it.

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